Polylysine is also called Epsilon Polylysine or ε-Polylysine.

  • Price:
  • Molecular Formula: (C6H12N2O)n
  • CAS: 25104-18-1/28211-04-3
  • HS: 3913900090



Usage:1.Preservative in food additive: The additive may be applied in bakery, confectionery, culinary, dairy, fruits and vegetables, meat, poultry, seafood as a preservative.

2.Toothbone for small dogs: Polylysine and Sodium Pyrophosphate are added to the toothbone to effectively prevent plaque from sticking to the teeth and keep the dog's breath fresh.

3.Antibacterial agents: Antibacterial agents in cosmetics: Oil Control Cleansing Foam, Ceramide Repair Cream, etc.

CAS#:25104-18-1/28211-04-3 HS NO.:3913900090  Packing:1kg*10 Per Carton /1kg*20 Per Carton

Shelf Life

2 year
with the original unopened package.





Light Yellow Color



Granule powder or Clumped


ε-Polylysine content, w/%

≥ 94


Loss on drying, w/%



Lead (Pb)/(mg/kg)



Total arsenic (calculated asAs)/(mg/kg)



Ash, w/%



Total plate count(CFU/g orCFU/ml)



colibacillus(CFU/g or CFU/ml)



Remark:We may make special specification according to customers requires.

ε-Polylysine is a food preservative manufactured from a fermentation process using Streptomyces albulus under aerobic conditions. It can inhibit the growth of Gram-positive and Gram-negative bacteria, yeasts, moulds, bacteria, etc.

ε-Polylysine is a homopolymer of L-lysine, one of the essential amino acids. It is linked by peptide bond formed with α-carboxyl of L-lysine and ε-azyl from other L-lysine.

ε-Polylysine is hygroscopic, light yellow power. It is soluble in water, slightly soluble in ethanol, insoluble in organic solvent such as ethyl acetate, ether, etc. The molecular of ε-Polylysine is a straight chain polymer of lysine. It can decompose to lysine in human body, and can be completely digested to absorption by the human body. ε-Polylysine can inhibit the growth of G+ and G- bacteria , yeast, mould, virus, etc., especially inhibit the G- bacteria which can’t be easily inhibited by other preservatives, such as E.coli, Salmonella, and also can inhibit the thermophilics, such as B,stearothermophilus. Its activity is not affected by pH, and stable when heated (120°C for 20min). Therefore, it can be sterilized along with the raw material.

However, ε-Polylysine antibacterial activity may be reduced due to the binding with acidic polysaccharides, hydrochlorides, phosphates, copper ions or others. ε-Polylysine antibacterial activity can be enhanced with hydrochloric acid, citric acid ,malic acid , glycine and higher fatty glycerides.

ε-Polylysine is food grade and meets FAO/WHO specifications. It is certified as GRAS (Generally Recognized As Safe) by the US FDA with US GRAS No.: GRN000135. Currently, ε-Polylysine has approval as a food additive in China, Korea, Japan, USA and some more countries.

Twin Chemical

                                                     EPL is Epsilon Polylysine      EPL HCL is Epsilon Polylysine HCL.

  1. EPL and EPL.HCL have different CAS: EPL CAS:25104-18-1    EPL.HCL CAS:28211-04-03

  2. EPL only have light yellow,but EPL.HCL has two colors:light yellow and white,normal our is white on picture above.

  3. the PH of EPL is 7-9,but EPL. HCL is 2.5-5.5, so their effects will be better in corresponding PH of end-product.

  4. So some company use EPL. HCL as EPL,because of the same color,different cas. But you can test the PH for identify.

                              Pls choose EPL or EPL HCL  according to above.